Sarcoidosis (sar - koy - sis) is a disease of unknown cause that leads to inflammation. This disease affects the body's organs. Normally, the immune system defends the body against foreign or harmful substances. For example, send special cells to protect the organs which are in danger. These cells release chemicals that recruit other cells to isolate and destroy the harmful substance. Inflammation occurs during this process. Once gone the harmful substance, cells and the inflammation disappears. People with Sarcoidosis, the inflammation does not go far. On the other hand, called some group of cells of the immune system to the granulomas form lumps (gran-yu-LO-MAS) in various organs of your body. OverviewSarcoidosis can affect any organ in your body. However, it is more likely to affect some bodies than others. The disease usually starts to lungs, skin or lymph nodes (especially the lymph nodes in the chest). In addition, the disease often affects eyes and liver. Although less common, Sarcoidosis can affect the heart and brain, leading to serious complications. If many granulomas form in an organ, they affect how the body functions. This can result in signs and symptoms. Signs and symptoms vary depending on the organs affected. Many people who have Sarcoidosis have signs or symptoms, or more gentle. Löfgren syndrome is a classic set of signs and symptoms that characterize some people I have Sarcoidosis. Löfgren syndrome can cause fever, lymph nodes, arthritis (usually in the ankles) or Erythema Nodosum (er-ih-el-but no: the sum). Erythema Nodosum is a skin rash of red or red-purple bumps sarcoidosis and remission on your ankles and Shins. The rash can be warm and tender to the touch. Treatment of sarcoidosis vary depending on the organs affected. Your doctor may prescribe topical or therapies to treat the disease of drug. Not everyone who has Sarcoidosis needs treatment. OutlookThe Outlook Sarcoidosis vary. Many people recover from the disease with little or no long-term problems. More than half of the people who have Sarcoidosis have been awarded within three years of diagnosis. Remission means that the disease is not checked, but may recur. Two-thirds of the people who have the disease have a discount to the 10 years of diagnosis. People who have Löfgren syndrome usually receive a discount. Relapse (return of the disease) 1 or more years after remission occurs in less than 5% of patients. Sarcoidosis leads to damage organs in about a third of people diagnosed with the disease. Damage can occur over the years and will involve more than one organ. Rarely, Sarcoidosis can be fatal. Death is usually the result of problems with the lungs, heart or brain. Poor results are probably more persons that have advanced disease and show improvement after treatment. Some people have an increased risk for bad outcomes of chronic (long-term) Sarcoidosis. This includes people who have scarring in the lungs, heart or brain complications or lupus pernio (LU-pus PUR - n). Lupus Pernio is a disease on the skin which can cause Sarcoidosis. Research is ongoing for new and better treatments for Sarcoidosis. Research is ongoing for new and better treatments for Sarcoidosis, etc.